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According to new studies, to spread in the other parts of the body, lung cancer cells use antioxidants by activating protein BACH1 and increasing the uptake and use of sugars. 

It is a well-known fact that cancer cells are exposed to oxidative stress caused by free oxygen radicals. Also, cancer cells are characterized by high uptake and use of sugar. 

When cancer cells metastasize to other parts of the body, they start reducing their oxidative stress, which can happen in two ways: the cancer cells can either obtain oxidants from the diet or synthesize their own. 
In about one in every three cases of lung cancer, the tumor cells have special mutations, linked to the NRF2 and KEAP1 genes, which enable them to start producing their own antioxidants.

It is when the protein BACH1 is stabilized and accumulates in the cancer cells.it stimulates metastasis mechanisms, including one that orders the cancer cells to increase both the metabolism of sugar into cell fuel and lactic acid, and the stockpiling of glucose from the blood stream

Lung cancer is the leading cause of cancer-related deaths worldwide. The most life-threatening aspect of lung cancer is metastasis.



Source : https://www.sciencedaily.com/releases/2019/06/190627114056.htm






















































































































































































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